Critics of clinical equipoise have long argued that it represents an overly permissive, and therefore morally unacceptable, mechanism for resolving the tensions inherent in clinical research. In particular, the equipoise requirement is often attacked on the grounds that it is not sufficiently responsive to the interests of individual patients. In this paper, we outline a view of equipoise that not only withstands a stronger version of this objection, which was recently articulated by Deborah Hellman, but also plays important roles in (...) clarifying the discussion. (shrink)

Over the last several decades there has been an increase in the amount of research conducted concerning academically dishonest behaviors at the undergraduate level. However, this research and subsequent interventions are based on the assumptions that there exists a clear understanding of what constitutes academic dishonesty. In an attempt to address this gap in the current literature, a concept synthesis of students’ perceptions of academic behavior was completed. The end result was 18 categories of potentially dishonest academic behaviors. Definitions and (...) examples are explored. Inter-rater reliability was completed and Kappa values are reported as well as implications for teaching and future research. (shrink)

Birdsong is widely analysed and discussed by people coming from both musical and scientific backgrounds. Both approaches provide valuable insight, but I argue that it is only through combining musical and scientific points of view, as well as perspectives from more tangentially related fields, that we can obtain the best possible understanding of birdsong. In this paper, I discuss how my own training as a musician, and in particular as a composer, affects how I listen to and parse birdsong. I (...) identify nine areas of overlap between human music and birdsong, which may serve as starting points both for musical and scientific analysis, as well as for interdisciplinary analysis as practiced in the developing field of “zoomusicology.” Using the hermit thrush (Catharus guttatus) as an example, I discuss how the song of a single species has been described by writers from a variety of disciplines, including music, literature, and the sciences, as well as how we can contextualise these varied perspectives in terms of broader cultural thought trends. I end with discussion of how combining approaches from multiple fields can help us to figure out new questions to ask, can help us identify how our own cultural biases may affect how we hear birdsong, and ultimately can help us develop richer and more nuanced understandings of the songs themselves. (shrink)

One of the assumptions of our legal system is that when a violation of law has occurred, we (society) should provide a remedy for individuals who were harmed. More specifically, we should provide them with corrective remedies—remedies that place them as nearly as possible in the position they would be in if no wrong had occurred. This principle is not universal. There are legal wrongs, usually statutory, for which only public officials can seek a judicial remedy. And where private remedies (...) do apply, not all the effects of a legal wrong are covered. But in general, individuals who have suffered legal wrongs are entitled to remedies that relieve the effects of the wrong and return them to their “rightful position.”. (shrink)

Theories of the genetics underlying punctuated equilibrium (PE) have been vague to date. Here the developmental gene hypothesis is proposed, which states that: 1) developmental regulatory (DevReg) genes are responsible for the orchestration of metazoan morphogenesis and their extreme conservation and mutation intolerance generates the equilibrium or stasis present throughout much of the fossil record and 2) the accumulation of regulatory elements and recombination within these same genes—often derived from transposable elements—drives punctuated bursts of morphological divergence and speciation across metazoa. (...) This two‐part hypothesis helps to explain the features that characterize PE, providing a theoretical genetic basis for the once‐controversial theory. Also see the video abstract here https://youtu.be/C-fu-ks5yDs. (shrink)

Visual narratives like comics often are used as materials in clinical testing under a belief that they are transparent materials for individuals who may struggle with language, such as those with autism spectrum disorder (ASD), developmental language disorder (DLD), or aphasia. This review shows that this “Visual Ease Assumption” is largely unsupported, warranting reconsideration of the ways visual narratives are used with clinical populations.

Focus on the evolutionary origins of musicality has been neglected relative to attention on language, so these new proposals are welcome stimulants. We argue for a broad comparative approach to understanding how the elements of musicality evolved, and against the use of overly simplistic evolutionary accounts.

The current model of adult neurogenesis in mammals suggests that adult‐born neurons are generated by stem cells that undergo long‐term self‐renewal, and that a lifetime supply of stem cells resides in the brain. In contrast, it has recently been demonstrated that adult‐born neurons in crayfish are generated by precursors originating in the immune system. This is particularly interesting because studies done many years ago suggest that a similar mechanism might exist in rodents and humans, with bone marrow providing stem cells (...) that can generate neurons. However, the relevance of these findings for natural mechanisms underlying adult neurogenesis in mammals is not clear, because of uncertainties at many levels. We argue here that the recent findings in crayfish send a strong signal to re‐examine existing data from rodents and humans, and to design new experiments that will directly test the contributions of the immune system to adult neurogenesis in mammals. (shrink)

We identify the significance and typical requirements of developmental analyses of the microbiome-gut-brain in parents, offspring, and parent-offspring relations, which have particular importance for neurobehavioral outcomes in mammalian species, including humans. We call for a focus on behavioral measures of social-emotional function. Methodological approaches to interpreting relations between the microbiota and behavior are discussed.

Alea, Bluck, Mroz and Edwards examine how the communication of autobiographical stories via face‐to‐face vs. instant message (IM) influences the extent to which social bonds form between strangers. The results of their study show that the in‐person communication of strangers’ autobiographical memories leads to greater engagement and higher empathy rates in the listener of those stories. That is, sharing autobiographical memories face‐to‐face (compared to IM) is positively correlated with positive feelings and closeness in the listener of those stories.

Relational reasoning is a complex form of human cognition involving the evaluation of relations between mental representations of information. Prior studies have modified stimulus properties of relational reasoning problems and examined differences in difficulty between different problem types. While subsets of these stimulus properties have been addressed in separate studies, there has not been a comprehensive study, to our knowledge, which investigates all of these properties in the same set of stimuli. This investigative gap has resulted in different findings across (...) studies which vary in task design, making it challenging to determine what stimulus properties make relational reasoning—and the putative formation of mental models underlying reasoning—difficult. In this article, we present the Multidimensional Relational Reasoning Task, a task which systematically varied an array of stimulus properties within a single set of relational reasoning problems. Using a mixed-effects framework, we demonstrate that reasoning problems containing a greater number of the premises as well as multidimensional relations led to greater task difficulty. The MRRT has been made publicly available for use in future research, along with normative data regarding the relative difficulty of each problem. (shrink)

Why do some groups succeed where others fail? We hypothesise that collaborative success is achieved when the relationship between the dyad's prior expertise and the complexity of the task creates a situation that affords constructive and interactive processes between group members. We call this state the zone of proximal facilitation in which the dyad's prior knowledge and experience enables them to benefit from both knowledge-based problem-solving processes (e.g., elaboration, explanation, and error correction) andcollaborative skills (e.g., creating common ground, maintaining joint (...) attention to the task). To test this hypothesis we conducted an experiment in which participants with different levels of aviation expertise, experts (flight instructors), novices (student pilots), and non-pilots, read flight problem scenarios of varying complexity and had to identify the problem and generate a solution with either another participant of the same level of expertise or alone. The non-pilots showed collaborative inhibition on problem identification in which dyads performed worse than their predicted potential for both simple and complex scenarios, whereas the novices and experts did not. On solution generation the non-pilot and novice dyads performed at their predicted potential with no collaborative inhibition on either simple or complex scenarios. In contrast, expert dyads showed collaborative gains, withdyads performing above their predicted potential, but only for the complex scenarios. On simple scenarios the expert dyads showed collaborative inhibition and performed worse than their predicted potential. We discuss the implications of these results for theories of collaborative problem solving. (shrink)

Mata and von Helversen's integrative review of adult age differences in search performance makes a good case that cognitive control may impact certain aspects of self-regulation of search. However, information foraging as a framework also offers an avenue to consider how adults of different ages adapt to age-related changes in cognition, such as in cognitive control.

The application of neuroimaging technology to the study of the injured brain has transformed how neuroscientists understand disorders of consciousness, such as the vegetative and minimally conscious states, and deepened our understanding of mechanisms of recovery. This scientific progress, and its potential clinical translation, provides an opportunity for ethical reflection. It was against this scientific backdrop that we convened a conference of leading investigators in neuroimaging, disorders of consciousness and neuroethics. Our goal was to develop an ethical frame to move (...) these investigative techniques into mature clinical tools. This paper presents the recommendations and analysis of a Working Meeting on Ethics, Neuroimaging and Limited States of Consciousness held at Stanford University during June 2007. It represents an interdisciplinary approach to the challenges posed by the emerging use of neuroimaging technologies to describe and characterize disorders of consciousness. (shrink)

BackgroundWhen conducting research with Indigenous populations consent should be sought from both individual participants and the local community. We aimed to search and summarise the literature about methods for seeking consent for research with Indigenous populations.MethodsA systematic literature search was conducted for articles that describe or evaluate the process of seeking informed consent for research with Indigenous participants. Guidelines for ethical research and for seeking consent with Indigenous people are also included in our review.ResultsOf 1447 articles found 1391 were excluded (...) ; 56 were relevant and included. Articles were categorised into original research that evaluated the consent process or publications detailing the process of seeking consent and guidelines for ethical research. Guidelines were categorised into international ; national and state/regional/local guidelines. In five studies based in Australia, Canada and The United States of America the consent process with Indigenous people was objectively evaluated. In 13 other studies interpreters, voice recording, videos, pictures, flipcharts and “plain language” forms were used to assist in seeking consent but these processes were not evaluated. Some Indigenous organisations provide examples of community-designed resources for seeking consent and describe methods of community engagement, but none are evaluated. International, national and local ethical guidelines stress the importance of upholding Indigenous values but fail to specify methods for engaging communities or obtaining individual consent. In the ‘Grey literature’ concerns about the consent process are identified but no solutions are offered.ConclusionConsultation with Indigenous communities is needed to determine how consent should be sought from the community and the individual, and how to evaluate this process. (shrink)

Healthcare workers experience moral injury (MI), a violation of their moral code due to circumstances beyond their control. MI threatens the healthcare workforce in all settings and leads to medical errors, depression/anxiety, and personal and occupational dysfunction, significantly affecting job satisfaction and retention. This article aims to differentiate concepts and define causes surrounding MI in healthcare. A narrative literature review was performed using SCOPUS, CINAHL, and PubMed for peer-reviewed journal articles published in English between 2017 and 2023. Search terms included (...) “moral injury” and “moral distress,” identifying 249 records. While individual risk factors predispose healthcare workers to MI, root causes stem from healthcare systems. Accumulation of moral stressors and potentially morally injurious events (PMIEs) (from administrative burden, institutional betrayal, lack of autonomy, corporatization of healthcare, and inadequate resources) result in MI. Individuals with MI develop moral resilience or residue, leading to burnout, job abandonment, and post-traumatic stress. Healthcare institutions should focus on administrative and climate interventions to prevent and address MI. Management should ensure autonomy, provide tangible support, reduce administrative burden, advocate for diversity of clinical healthcare roles in positions of interdisciplinary leadership, and communicate effectively. Strategies also exist for individuals to increase moral resilience, reducing the impact of moral stressors and PMIEs. (shrink)

Over the course of human life, health care decision‐making is often interdependent. In this article, we use “interdependence” to refer to patients’ engagement of nonclinicians—for example, family members or trusted friends—to reach health care decisions. Interdependence, we suggest, is common for patients in all stages of life, from early childhood to late adulthood. This view contrasts with the common bioethical assumption that medical decisions are either wholly independent or dependent and that independence or dependence is tightly coupled with a person's (...) decision‐making capacity. In this article, we array various approaches to decision‐making along a continuum of interdependence. An appreciation of this continuum can empower patients and elucidate ethical challenges that arise when people transition between different kinds of interdependence across the life span. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Explorations in the Theology of Benedict XVI ed. by John C. CavadiniJeffrey L. MorrowExplorations in the Theology of Benedict XVI. Edited by John C. Cavadini. Notre Dame, Ind.: University of Notre Dame Press, 2012. Pp. viii + 318. $30.00 (cloth). ISBN: 978-0-268-02309-6.Pope Emeritus Benedict XVI is arguably the greatest theologian to ascend to the chair of St. Peter in centuries. His theological output even prior to becoming pope (...) is staggering. It is thus fitting that an edited volume examine his theological oeuvre; there is a need for many more such volumes. The essays collected in this book were originally presented at a conference on the theology of Pope Benedict at the University of Notre Dame. Each contribution brings something insightful and unique to the volume. The book is divided into three sections: “The Dynamic of Advent,” encompassing chapters 2–5; “Caritas in Veritate,” encompassing chapters 6–7; and “God is Love,” encompassing the remaining chapters 8–11. The initial chapter-length introduction and the first chapter fall outside of this division because in many ways they set the stage for the entire volume.John Cavadini’s introduction (1–20) could serve as a useful overview of the theological work of Pope Benedict. Cavadini provides a preview of each chapter but also underscores the significance of Benedict’s theological work. He emphasizes how “one of Benedict’s major achievements is the demonstration of Augustine’s original insight into the unity of the theological tasks of understanding and of engendering understanding” (3).Cyril O’Regan’s very fine essay, “Benedict the Augustinian” (21–60), examines the Augustinian nature of Benedict’s theology. O’Regan maintains, “throughout his career Benedict not only turns again and again to Augustine as his theological model, but also... in Benedict’s self-understanding[,] the basic figuration of his theology is Augustinian” (22). This Augustinian texture to Benedict’s theology involves, among other things, his “real familiarity with and admiration” for “the classic” works of Augustine, his use of Augustine’s “theological style,” his use of shared themes, and the manner in which he consciously “articulates substantive theological positions” typical of Augustine. Moreover, O’Regan points to “Benedict’s sense that he is living in a time of crisis and senescence similar to that of Augustine” (21–22). Some of the similarities O’Regan observes in the theological work of Augustine and Benedict pertain to eschatology, the relationship between faith and reason, biblical interpretation, culture, the role of the liturgy, and the centrality of prayer. O’Regan’s essay is undoubtedly the best piece I have read on the importance of Augustine for Benedict.The thesis of Peter Casarella’s “Culture and Conscience in the Thought of Joseph Ratzinger/Pope Benedict XVI” (63–86) is that for Benedict, “the witness to truth is the key to seeing how culture and conscience are necessarily intertwined” (64). Casarella initiates his investigation with the pope’s critique of relativism. The first major section examines what he terms Benedict’s “theology of culture.” For Benedict, this has a moral dimension, and thus [End Page 493] Caserella spends the entire second portion of his essay looking at conscience and its formation in the context of culture. This is a very helpful essay that makes an important contribution to Benedict’s thought as it relates to moral theology.The late Fr. Edward Oakes’s contribution, “Resolving the Relativity Paradox: Pope Benedict XVI and the Challenge of Christological Relativism” (87–113), explores Benedict’s problem with relativism, but homes in on relativism in the context of Christology. Oakes argues, “the challenge of relativism cannot be met unless it is done first and foremost in Christological terms” (93), and he thinks Benedict does precisely this. Oakes’s overview of Ernst Troeltsch’s discussion of historical criticism as corrosive to Christology is enlightening:what most undermines Christocentrism is the historical-critical method, not so much because of the results arising from that method as from its very use.... Historical criticism... is marked by three key methodological principles: (1) the principle of criticism, that no historical document... can be taken on its own terms as automatically reliable but must... (shrink)

The consent and community engagement process for research with Indigenous communities is rarely evaluated. Research protocols are not always collaborative, inclusive or culturally respectful. If participants do not trust or understand the research, selection bias may occur in recruitment, affecting study results potentially denying participants the opportunity to provide more knowledge and greater understanding about their community. Poorly informed consent can also harm the individual participant and the community as a whole. Invited by local Aboriginal community leaders of the Fitzroy (...) Valley, the Kimberley, Western Australia, The Picture Talk project explores the consent process for research. Focus groups of Aboriginal community members were conducted to establish preferences for methods of seeking individual consent. Transcripts were analysed through NVivo10 Qualitative software using grounded theory with inductive and deductive coding. Themes were synthesised with quotes highlighted. Focus groups with Aboriginal community members were facilitated by a Community Navigator as a cultural guide and interpreter and a researcher. Participants were recruited from all main language groups of the Fitzroy Valley – Gooniyandi, Walmajarri, Wangkatjungka, Bunuba and Nikinya. Participants were aged ≥18 years, with 5 female groups and one male group. Themes identified include: Reputation and trust is essential; The Community Navigator is key; Pictures give the words meaning – milli milli versus Pictures; Achieving consensus in circles; Signing for consent; and Research is needed in the Valley. Aboriginal communities of the Fitzroy Valley recommend that researchers collaborate with local leaders, develop trust and foster a good reputation in the community prior to research. Local Aboriginal researchers should be employed to provide cultural guidance throughout the research process and interpret local languages especially for elders. Pictures are preferred to written text to explain research information and most prefer to sign for consent. The Fitzroy Valley welcomes research when collaborative and for the benefit of the community. Future research could include exploring how to support young people, promote health screening and improve understanding of medical knowledge. (shrink)

This article contrasts St. Thomas More's theoretical work on the role of faith and history in biblical exegesis with that of Fr. Richard Simon. I argue that, although Simon's work appears to be a critique of his more skeptical contemporaries like Hobbes and Spinoza, in reality he is carrying their work forward. I argue that More's union of faith and reason, theology and history, is more promising than Simon's for Catholic theological biblical exegesis.

With the 1901 publication of his Les Mythes babyloniens et les premiers chapitres de la Genèse, the French Catholic scholar Alfred Loisy examined carefully parallels between Babylonian literature and the Book of Genesis. In German scholarship, this had been a growing fascination since at least the 1895 publication of Hermann Gunkel’s Schöpfung und Chaos in Urzeit und Endzeit. Loisy’s use of the concept of “Myth” provides an important window into the appropriation of German scholarship on religion and the Bible into (...) the French scholarly world. Through Loisy’s work, what had been primarily a German Protestant academic discussion became one of the matchsticks that ignited what would become known as the Roman Catholic Modernist Crisis. This present article situates Loisy’s appropriation of “Myth” from the German scholarship he mastered within the proximate cultural, historical, and religious context that became Roman Catholic Modernism. (shrink)

Thomas More presents us with a wonderful example of martyrological exegesis where his exegetical work was intended to inspire his readers to live the virtues, to follow Christ, and to provide consolation amidst tribulation. Such exegesis aimed to aid the reader to live the martyrdom required in ordinary life and beyond that, if necessary, with mental anguish, physical torture, and even death on behalf of Christ. Before examining More's work, I first situate this discussion within the broader conversation concerning modern (...) biblical interpretation- in particular the notion of senses of Scripture - therein explaining how I shall be using terms like mystagogy and martyrdom in this article. I shall then examine More's spiritual exegesis of Jesus' passion narratives, paying particular attention to the agony in the garden. I shall conclude with a look at the saint's life, which provides a background for his interpretation of Scripture. (shrink)

In this commentary, we set out the specifics of how Glowacki's game theoretical framework for the evolution of peace could be incorporated within broader cultural evolutionary approaches. We outline a formal proposal for prisoner's dilemma games investigating raid-based conflict. We also centre an ethnographic lens to understand the norms surrounding war and peace in intergroup interactions in small-scale communities.

This article examines five different Medical-Legal Partnerships associated with Yale Law School in New Haven, Connecticut to illustrate how MLP addresses the social determinants of poor health. These MLPs address varied and distinct health and legal needs of unique patient populations, including: 1) children; 2) immigrants; 3) formerly incarcerated individuals; 4) patients with cancer in palliative care; and 5) veterans. The article charts a research agenda to create the evidence base for quality and evaluation metrics, capacity building, sustainability, and best (...) practices; it also focuses specifically on a research agenda that identifies the value of the lawyers in MLP. Such a focus on the “L” has been lacking and is overdue. (shrink)